Mesenchymal Stromal Cells Engage Complement and Complement Receptor Bearing Innate Effector Cells to Modulate Immune Responses

Infusion of human third-party mesenchymal stromal cells (MSCs) appears to be a promising therapy for acute graft-versus-host disease (aGvHD). To date, little is known about how MSCs interact with the body's innate immune system after clinical infusion. This study shows, that exposure of MSCs to...

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Detalhes bibliográficos
Main Authors: Moll, Guido, Jitschin, Regina, von Bahr, Lena, Rasmusson-Duprez, Ida, Sundberg, Berit, Lönnies, Lena, Elgue, Graciela, Nilsson-Ekdahl, Kristina, Mougiakakos, Dimitrios, Lambris, John D., Ringdén, Olle, Le Blanc, Katarina, Nilsson, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128611/
https://ncbi.nlm.nih.gov/pubmed/21747949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021703
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