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SNaPshot and StripAssay as Valuable Alternatives to Direct Sequencing for KRAS Mutation Detection in Colon Cancer Routine Diagnostics

Although direct sequencing is the gold standard for KRAS mutation detection in routine diagnostics, it remains laborious, time consuming, and not very sensitive. Our objective was to evaluate SNaPshot and the KRAS StripAssay as alternatives to sequencing for KRAS mutation detection in daily practice...

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Hlavní autoři: Fariña Sarasqueta, Arantza, Moerland, Elna, de Bruyne, Hanneke, de Graaf, Henk, Vrancken, Tamara, van Lijnschoten, Gesina, van den Brule, Adriaan J.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128574/
https://ncbi.nlm.nih.gov/pubmed/21354055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2010.10.006
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