Construction of uricase-overproducing strains of Hansenula polymorpha and its application as biological recognition element in microbial urate biosensor

BACKGROUND: The detection and quantification of uric acid in human physiological fluids is of great importance in the diagnosis and therapy of patients suffering from a range of disorders associated with altered purine metabolism, most notably gout and hyperuricaemia. The fabrication of cheap and re...

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Bibliografiska uppgifter
Huvudupphovsmän: Dmytruk, Kostyantyn V, Smutok, Oleh V, Dmytruk, Olena V, Schuhmann, Wolfgang, Sibirny, Andriy A
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128571/
https://ncbi.nlm.nih.gov/pubmed/21612631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-58
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