Activation of autophagy in mesenchymal stem cells provides tumor stromal support

Recent studies have implicated multipotential mesenchymal stem cells (MSCs) as an aid to breast cancer cell proliferation and metastasis, partly as a result of the MSCs secretome. As the tumor gets beyond 2 mm in diameter, the stromal cells could undergo starvation due to the lack of sufficient nutr...

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Autori principali: Sanchez, Cecilia G., Penfornis, Patrice, Oskowitz, Adam Z., Boonjindasup, Aaron G., Cai, David Z., Dhule, Santosh S., Rowan, Brian G., Kelekar, Ameeta, Krause, Diane S., Pochampally, Radhika R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Cancer Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128555/
https://ncbi.nlm.nih.gov/pubmed/21317300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr029
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