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Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

Chromosomal double-strand breaks (DSBs) in mammalian cells are repaired by either homology-directed repair (HDR), using a homologous sequence as a repair template, or nonhomologous end-joining (NHEJ), which often involves sequence alterations at the DSB site. To characterize the interrelationship of...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Pierce, Andrew J., Hu, Peng, Han, Mingguang, Ellis, Nathan, Jasin, Maria
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312854/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11751629/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.946401
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