Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins

The anaphase-promoting complex/cyclosome (APC) ubiquitin ligase is activated by Cdc20 and Cdh1 and inhibited by Mad2 and the spindle assembly checkpoint complex, Mad2B, and the early mitotic inhibitor Emi1. Mad2 inhibits APC(Cdc20), whereas Mad2B preferentially inhibits APC(Cdh1). We have examined t...

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Détails bibliographiques

Publié dans:	Genes Dev
Auteurs principaux:	Reimann, Julie D.R., Gardner, Bryan E., Margottin-Goguet, Florence, Jackson, Peter K.
Format:	Artigo
Langue:	Inglês
Publié:	Cold Spring Harbor Laboratory Press 2001
Sujets:	Research Paper
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11751633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.945701
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