Depletion of CD25(+) T cells from hematopoietic stem cell grafts increases posttransplantation vaccine-induced immunity to neuroblastoma

A multifaceted immunotherapeutic strategy that includes hematopoietic stem cell (HSC) transplantation, T-cell adoptive transfer, and tumor vaccination can effectively eliminate established neuroblastoma tumors in mice. In vivo depletion of CD4(+) T cells in HSC transplantation recipients results in...

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Hlavní autoři: Jing, Weiqing, Yan, Xiaocai, Hallett, William H. D., Gershan, Jill A., Johnson, Bryon D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128485/
https://ncbi.nlm.nih.gov/pubmed/21521781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-326108
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