Administration of PPARβ/δ agonist reduces copper-induced liver damage in mice: possible implications in clinical practice

In this study we investigated if peroxisome proliferator-activated receptor β/δ activation protects from copper-induced acute liver damage. Mice treated with copper had significant body weight loss, serum alanine aminotransferase increase, modest changes in liver histology, increase of tumor necrosi...

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Главные авторы: Sanchez-Siles, Alvaro A., Ishimura, Norihisa, Rumi, Mohammad A. K., Tamagawa, Yuji, Ito, Satoko, Ishihara, Shunji, Nabika, Toru, Kinoshita, Yoshikazu
Формат: Artigo
Язык:Inglês
Опубликовано: the Society for Free Radical Research Japan 2011
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128365/
https://ncbi.nlm.nih.gov/pubmed/21765606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.10-139
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