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The nature of intestinal stem cells' nurture

Mustata et al demonstrate in this issue of EMBO reports that Lgr4 expression in the stem cells and transit amplifying cells of the intestinal crypts is required for the establishment of the stem cell niche and also for the maintenance of intestinal stem cells in ex vivo organoid cultures.

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Bibliografiske detaljer
Main Authors: Roth, Sabrina, Fodde, Riccardo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128296/
https://ncbi.nlm.nih.gov/pubmed/21566649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.97
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