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Cease and desist: modulating short-range Dpp signalling in the stem-cell niche

Drosophila ovarian germline stem cells (GSCs) are maintained by the extracellular BMP2/4 orthologue Dpp, which is produced from the surrounding somatic niche. The Dpp signal has a short range; it induces a response in GSCs within the niche, but is rapidly extinguished in their progeny only one cell-...

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Detalhes bibliográficos
Main Authors: Harris, Robin E, Ashe, Hilary L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128284/
https://ncbi.nlm.nih.gov/pubmed/21546910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.80
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