An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease

BACKGROUND: Chronic lymphocytic leukemia cells are characterized by an apparent longevity in vivo which is lost when they are cultured in vitro. Cellular interactions and factors provided by the microenvironment appear essential to cell survival and may protect leukemic cells from the cytotoxicity o...

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Detalhes bibliográficos
Main Authors: Giannoni, Paolo, Scaglione, Silvia, Quarto, Rodolfo, Narcisi, Roberto, Parodi, Manuela, Balleari, Enrico, Barbieri, Federica, Pattarozzi, Alessandra, Florio, Tullio, Ferrini, Silvano, Corte, Giorgio, de Totero, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128221/
https://ncbi.nlm.nih.gov/pubmed/21486864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.029736
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