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The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor

The mammalian hairless (hr) gene plays a critical role in the maintenance of hair growth. Although the hr gene has been identified, the biochemical function of its encoded protein (Hr) has remained obscure. Here, we show that Hr functions as a transcriptional corepressor for thyroid hormone receptor...

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Detalhes bibliográficos
Publicado no:Genes Dev
Principais autores: Potter, Gregory B., Beaudoin, Gerard M.J., DeRenzo, Cynthia L., Zarach, Joanna M., Chen, Steve H., Thompson, Catherine C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312820/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11641275/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.916701
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