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Investigating population stratification and admixture using eigenanalysis of dense genotypes

Principal components analysis of genetic data is used to avoid inflation in type I error rates in association testing due to population stratification by covariate adjustment using the top eigenvectors and to estimate cluster or group membership independent of self-reported or ethnic identities. Eig...

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Hlavní autor: Shriner, D
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128175/
https://ncbi.nlm.nih.gov/pubmed/21448230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/hdy.2011.26
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