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Calcium signaling in systemic lupus erythematosus T cells: a treatment target

OBJECTIVE: Systemic lupus erythematosus (SLE) T cells display a hyperactive calcineurin-NFAT pathway. The aim of this study is to answer whether this pathway is responsible for the aberrant SLE T cell function and test the effectiveness of the recently recognized calcineurin inhibitor dipyridamole i...

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Autors principals: Kyttaris, Vasileios C., Zhang, Zheng, Kampagianni, Ourania, Tsokos, George C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128171/
https://ncbi.nlm.nih.gov/pubmed/21437870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30353
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