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Whi3 binds the mRNA of the G(1) cyclin CLN3 to modulate cell fate in budding yeast

Eukaryotic cells commit in G(1) to a new mitotic cycle or to diverse differentiation processes. Here we show that Whi3 is a negative regulator of Cln3, a G(1) cyclin that promotes transcription of many genes to trigger the G(1)/S transition in budding yeast. Whi3 contains an RNA-recognition motif th...

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Udgivet i:Genes Dev
Principais autores: Garí, Eloi, Volpe, Tom, Wang, Hongyin, Gallego, Carme, Futcher, Bruce, Aldea, Martí
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2001
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312816/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11691832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.203501
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