NFκB1 and NFκBIA Polymorphisms Are Associated with Increased Risk for Sporadic Colorectal Cancer in a Southern Chinese Population

BACKGROUND: Nuclear factor κB (NFκB) plays a key role in the regulation of apoptosis. The function of NFκB is inhibited by binding to NFκB inhibitor (IκB), and disruption of the balance of NFκB and IκB is related to the development of many diseases, including tumors. Therefore, we hypothesized that...

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Detalhes bibliográficos
Main Authors: Song, Shunxin, Chen, Dianke, Lu, Jiachun, Liao, Jiawei, Luo, Yanxin, Yang, Zuli, Fu, Xinhui, Fan, Xinjuan, Wei, Yisheng, Yang, Lei, Wang, Lei, Wang, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128094/
https://ncbi.nlm.nih.gov/pubmed/21738780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021726
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