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A canine model of Cohen syndrome: Trapped Neutrophil Syndrome

BACKGROUND: Trapped Neutrophil Syndrome (TNS) is a common autosomal recessive neutropenia in Border collie dogs. RESULTS: We used a candidate gene approach and linkage analysis to show that the causative gene for TNS is VPS13B. We chose VPS13B as a candidate because of similarities in clinical signs...

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Detalhes bibliográficos
Main Authors: Shearman, Jeremy R, Wilton, Alan N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128065/
https://ncbi.nlm.nih.gov/pubmed/21605373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-258
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