Epithelial to Mesenchymal Transition by TGFβ-1 Induction Increases Stemness Characteristics in Primary Non Small Cell Lung Cancer Cell Line

BACKGROUND: Cancer Stem Cells (CSCs) hypothesis asserts that only a small subset of cells within a tumour is capable of both tumour initiation and sustainment. The Epithelial-Mesenchymal Transition (EMT) is an embryonic developmental program that is often activated during cancer invasion and metasta...

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Detalhes bibliográficos
Main Authors: Pirozzi, Giuseppe, Tirino, Virginia, Camerlingo, Rosa, Franco, Renato, La Rocca, Aantonello, Liguori, Eleonora, Martucci, Nicola, Paino, Francesca, Normanno, Nicola, Rocco, Gaetano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128060/
https://ncbi.nlm.nih.gov/pubmed/21738704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021548
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