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Functional overlap between Sgs1–Top3 and the Mms4–Mus81 endonuclease

The RecQ DNA helicases, human BLM and yeast Sgs1, form a complex with topoisomerase III (Top3) and are thought to act during DNA replication to restart forks that have paused due to DNA damage or topological stress. We have shown previously that yeast cells lacking SGS1 or TOP3 require MMS4 and MUS8...

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Détails bibliographiques
Auteurs principaux: Kaliraman, Vivek, Mullen, Janet R., Fricke, William M., Bastin-Shanower, Suzanne A., Brill, Steven J.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC312806/
https://ncbi.nlm.nih.gov/pubmed/11641278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.932201
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