Functional characterization of human Cd33(+ )And Cd11b(+ )myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines

BACKGROUND: Tumor immune tolerance can derive from the recruitment of suppressor cell populations, including myeloid-derived suppressor cells (MDSC). In cancer patients, MDSC accumulation correlates with increased tumor burden, but the mechanisms of MDSC induction remain poorly understood. METHODS:...

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Detalhes bibliográficos
Main Authors: Lechner, Melissa G, Megiel, Carolina, Russell, Sarah M, Bingham, Brigid, Arger, Nicholas, Woo, Tammy, Epstein, Alan L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128058/
https://ncbi.nlm.nih.gov/pubmed/21658270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-90
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