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Pros and cons of a prion-like pathogenesis in Parkinson's disease

BACKGROUND: Parkinson's disease (PD) is a slowly progressive neurodegenerative disorder which affects widespread areas of the brainstem, basal ganglia and cerebral cortex. A number of proteins are known to accumulate in parkinsonian brains including ubiquitin and α-synuclein. Prion diseases are...

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Hlavní autoři: Hilker, Ruediger, Brotchie, Jonathan M, Chapman, Joab
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128002/
https://ncbi.nlm.nih.gov/pubmed/21689433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-11-74
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