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Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast

The retrograde movement of tRNAs from the cytoplasm to the nucleus occurs constitutively in eukaryotic cells but its functional significance remains unclear. We show evidence suggesting that in Saccharomyces cerevisiae, a spliced tRNA precursor must be imported into the nucleus before the biogenesis...

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Detalles Bibliográficos
Main Authors: Ohira, Takayuki, Suzuki, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127885/
https://ncbi.nlm.nih.gov/pubmed/21670254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105645108
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