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Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis

The RET receptor tyrosine kinase has a critical role in kidney organogenesis and the development of the enteric nervous system. Two major isoforms, RET9 and RET51, differ in the amino acid sequence of the C-terminal tail as a result of alternative splicing. To determine the roles of these isoforms i...

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Udgivet i:Genes Dev
Principais autores: de Graaff, Esther, Srinivas, Shankar, Kilkenny, Carol, D'Agati, Vivette, Mankoo, Baljinder S., Costantini, Frank, Pachnis, Vassilis
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2001
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11562352/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.205001
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