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Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32)
BACKGROUND: Elevated numbers of regulatory T cells (T(regs)) have been implicated in certain cancers. Depletion of T(regs )has been shown to increase anti-tumor immunity. T(regs )also play a critical role in the suppression of autoimmune responses. The study of T(regs )has been hampered by a lack of...
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Päätekijät: | , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
BioMed Central
2011
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127830/ https://ncbi.nlm.nih.gov/pubmed/21615933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-27 |
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