Signal peptide cleavage is essential for surface expression of a regulatory T cell surface protein, leucine rich repeat containing 32 (LRRC32)

BACKGROUND: Elevated numbers of regulatory T cells (T(regs)) have been implicated in certain cancers. Depletion of T(regs )has been shown to increase anti-tumor immunity. T(regs )also play a critical role in the suppression of autoimmune responses. The study of T(regs )has been hampered by a lack of...

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Detalhes bibliográficos
Main Authors: Chan, Derek V, Somani, Ally-Khan, Young, Andrew B, Massari, Jessica V, Ohtola, Jennifer, Sugiyama, Hideaki, Garaczi, Edina, Babineau, Denise, Cooper, Kevin D, McCormick, Thomas S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127830/
https://ncbi.nlm.nih.gov/pubmed/21615933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-12-27
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