Evaluation of the proliferation markers Ki-67/MIB-1, mitosin, survivin, pHH3, and DNA topoisomerase IIα in human anaplastic astrocytomas - an immunohistochemical study

BACKGROUND: Histological malignancy grading of astrocytomas can be challenging despite criteria given by the World Health Organisation (WHO). Grading is fundamental for optimal prognostication and treatment, and additional biomarkers are needed to support the histopathological diagnosis. Estimation...

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Hauptverfasser: Habberstad, Andreas H, Gulati, Sasha, Torp, Sverre H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127815/
https://ncbi.nlm.nih.gov/pubmed/21609421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-6-43
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