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Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes

Imprinting of the maternally-expressed Igf2r gene is controlled by an intronic imprint control element (ICE) known as Region2 that contains the promoter of the noncoding Air RNA, whose transcript overlaps the silenced paternal Igf2r promoter in an antisense orientation. Two novel imprinted genes, Sl...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Zwart, Ronald, Sleutels, Frank, Wutz, Anton, Schinkel, Alfred H., Barlow, Denise P.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312779/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11562346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.206201
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