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Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation
The Myc protein binds DNA and activates transcription by mechanisms that are still unclear. We used chromatin immunoprecipitation (ChIP) to evaluate Myc-dependent changes in histone acetylation at seven target loci. Upon serum stimulation of Rat1 fibroblasts, Myc associated with chromatin, histone H...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312758/ https://ncbi.nlm.nih.gov/pubmed/11511539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.906601 |
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