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Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation

The Myc protein binds DNA and activates transcription by mechanisms that are still unclear. We used chromatin immunoprecipitation (ChIP) to evaluate Myc-dependent changes in histone acetylation at seven target loci. Upon serum stimulation of Rat1 fibroblasts, Myc associated with chromatin, histone H...

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Detalhes bibliográficos
Main Authors: Frank, Scott R., Schroeder, Marianne, Fernandez, Paula, Taubert, Stefan, Amati, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312758/
https://ncbi.nlm.nih.gov/pubmed/11511539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.906601
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