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Binding Sites for Bilobalide, Diltiazem, Ginkgolide, and Picrotoxinin at the 5-HT(3) Receptor

Bilobalide (BB), ginkgolide B (GB), diltiazem (DTZ), and picrotoxinin (PXN) are 5-hydroxytryptamine type 3 (5-HT(3)) receptor antagonists in which the principal sites of action are in the channel. To probe their exact binding locations, 5-HT(3) receptors with substitutions in their pore lining resid...

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Detalhes bibliográficos
Main Authors: Thompson, A. J., Duke, R. K., Lummis, S. C. R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127528/
https://ncbi.nlm.nih.gov/pubmed/21505038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.071415
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