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A Q63E Rhodobacter sphaeroides AppA BLUF domain mutant is locked in a pseudo light-excited signaling state

The AppA BLUF photoreceptor from Rhodobacter sphaeroides contains a conserved key residue, Gln63 that is thought to undergo a shift in hydrogen bonding interactions when a bound flavin is light excited. In this study we have characterized two substitution mutants of Gln63 (Q63E, Q63L) in the context...

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Autori principali: Dragnea, Vladimira, Arunkumar, Alphonse I., Lee, Chul Won, Giedroc, David P., Bauer, Carl E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127458/
https://ncbi.nlm.nih.gov/pubmed/21082791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1002162
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