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High efficacy of a Listeria-based vaccine against metastatic breast cancer reveals a dual mode of action
Most cancer vaccines induce cytotoxic T lymphocyte (CTL) responses to tumor-associated antigens (TAA). Killing of tumor cells occurs through TAA-specific CTL-mediated cytolysis. Here we show that one preventive followed by two therapeutic immunizations with an attenuated Listeria monocytogenes (LM)-...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127451/ https://ncbi.nlm.nih.gov/pubmed/19584282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4855 |
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