Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

Triple-negative breast cancer (TNBC) is a highly diverse group of cancers, and subtyping is necessary to better identify molecular-based therapies. In this study, we analyzed gene expression (GE) profiles from 21 breast cancer data sets and identified 587 TNBC cases. Cluster analysis identified 6 TN...

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Main Authors: Lehmann, Brian D., Bauer, Joshua A., Chen, Xi, Sanders, Melinda E., Chakravarthy, A. Bapsi, Shyr, Yu, Pietenpol, Jennifer A.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2011
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127435/
https://ncbi.nlm.nih.gov/pubmed/21633166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45014
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