The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

We describe a novel mammalian DNA binding activity that requires at least two symmetrically methylated CpG dinucleotides in its recognition sequence, preferably within the sequence 5′CGCG. A key component of the activity is Kaiso, a protein with POZ and zinc-finger domains that is known to associate...

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Detalhes bibliográficos
Main Authors: Prokhortchouk, Anna, Hendrich, Brian, Jørgensen, Helle, Ruzov, Alexei, Wilm, Matthias, Georgiev, Georgii, Bird, Adrian, Prokhortchouk, Egor
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312733/
https://ncbi.nlm.nih.gov/pubmed/11445535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.198501
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