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TLR4-mediated autophagy in macrophages is a p62-dependent type of selective autophagy of aggresome-like induced structures (ALIS)

Autophagy plays an evolutionarily conserved role in host defense against pathogens. Autophagic protection mechanisms against microbes range from regulating immune signaling responses to directly targeting the pathogens for lysosomal degradation. Toll-like receptors (TLR s) that detect conserved mole...

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Detalhes bibliográficos
Main Authors: Fujita, Ken-Ichi, Srinivasula, Srinivasa M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127216/
https://ncbi.nlm.nih.gov/pubmed/21412052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.5.15101
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