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A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene
casanova (cas) mutant zebrafish embryos lack endoderm and develop cardia bifida. In a substractive screen for Nodal-responsive genes, we isolated an HMG box-containing gene, 10J3, which is expressed in the endoderm. The cas phenotype is rescued by overexpression of 10J3 and can be mimicked by 10J3-d...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312720/ https://ncbi.nlm.nih.gov/pubmed/11410529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.196901 |
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