A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene

casanova (cas) mutant zebrafish embryos lack endoderm and develop cardia bifida. In a substractive screen for Nodal-responsive genes, we isolated an HMG box-containing gene, 10J3, which is expressed in the endoderm. The cas phenotype is rescued by overexpression of 10J3 and can be mimicked by 10J3-d...

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Autores principales: Dickmeis, Thomas, Mourrain, Philippe, Saint-Etienne, Laure, Fischer, Nadine, Aanstad, Pia, Clark, Matthew, Strähle, Uwe, Rosa, Frédéric
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
Materias:
Research Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC312720/
https://ncbi.nlm.nih.gov/pubmed/11410529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.196901
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