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Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females

RATIONALE: Although pre-menopausal females have a lower risk for cardiovascular disease, the mechanism(s) are poorly understood. OBJECTIVE: We tested the hypothesis that cardioprotection in females is mediated by altered mitochondrial protein levels and/or post-translational modifications. METHODS A...

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Detalhes bibliográficos
Main Authors: Lagranha, Claudia J, Deschamps, Anne, Aponte, Angel, Steenbergen, Charles, Murphy, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127199/
https://ncbi.nlm.nih.gov/pubmed/20413785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.213645
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