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Antagonistic crosstalk between APC and HIF-1α
Most colorectal cancers have mutations in the tumor suppressor APC. The best-understood function of APC is its participation in a protein complex that regulates the availability of β-catenin. Solid tumors are characterized by the presence of hypoxia as well as inflammation, which leads to the upregu...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127156/ https://ncbi.nlm.nih.gov/pubmed/21502812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.10.15638 |
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