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Down-regulation of tTG expression by RNAi inhibits HSC proliferation and attenuates liver fibrosis

Purpose: Expressed in hepatic stellate cell (HSC), tTG is involved in fibrotic diseases including human hepatic fibrosis by promoting the cross-linking of ECM and participating in the initiation and/or progression of liver fibrosis. The purpose of this study is to identify whether depletion of tTG c...

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Detalhes bibliográficos
Main Authors: Zhao, Gang, Zhang, Zhi-Qi, Zhang, Bin, Luo, Meng, Sun, Yong-Wei, Wu, Zhi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127072/
https://ncbi.nlm.nih.gov/pubmed/21738822
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