Characterization of macroautophagic flux in vivo using a leupeptin-based assay

Macroautophagy is a highly conserved catabolic process that is crucial for organ homeostasis in mammals. However, methods to directly measure macroautophagic activity (or flux) in vivo are limited. In this study we developed a quantitative macroautophagic flux assay based on measuring LC3b protein t...

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Detaylı Bibliyografya
Asıl Yazarlar: Haspel, Jeffrey, Shaik, Rahamthulla S, Ifedigbo, Emeka, Nakahira, Kiichi, Dolinay, Tamas, Englert, Joshua A, Choi, Augustine M K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2011
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Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127049/
https://ncbi.nlm.nih.gov/pubmed/21460622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.6.15100
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