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Escherichia coli K5 heparosan fermentation and improvement by genetic engineering
N-acetyl heparosan is the precursor for the biosynthesis of the important anticoagulant drug heparin. The Escherichia coli K5 capsular heparosan polysaccharide provides a promising precursor for in vitro chemoenzymatic production of bioengineered heparin. This article explores the improvements of he...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3127022/ https://ncbi.nlm.nih.gov/pubmed/21636991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.2.1.14201 |
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