Sharp, an inducible cofactor that integrates nuclear receptor repression and activation

A yeast two-hybrid screen using the conserved carboxyl terminus of the nuclear receptor corepressor SMRT as a bait led to the isolation of a novel human gene termed SHARP (SMRT/HDAC1 Associated Repressor Protein). SHARP is a potent transcriptional repressor whose repression domain (RD) interacts dir...

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Autores principales: Shi, Yanhong, Downes, Michael, Xie, Wen, Kao, Hung-Ying, Ordentlich, Peter, Tsai, Chih-Cheng, Hon, Michelle, Evans, Ronald M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2001
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC312688/
https://ncbi.nlm.nih.gov/pubmed/11331609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.871201
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