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A Beta-mixture model for dimensionality reduction, sample classification and analysis

BACKGROUND: Patterns of genome-wide methylation vary between tissue types. For example, cancer tissue shows markedly different patterns from those of normal tissue. In this paper we propose a beta-mixture model to describe genome-wide methylation patterns based on probe data from methylation microar...

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Autori principali: Laurila, Kirsti, Oster, Bodil, Andersen, Claus L, Lamy, Philippe, Orntoft, Torben, Yli-Harja, Olli, Wiuf, Carsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126746/
https://ncbi.nlm.nih.gov/pubmed/21619656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-215
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