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Adaptive molecular evolution of the Major Histocompatibility Complex genes, DRA and DQA, in the genus Equus

BACKGROUND: Major Histocompatibility Complex (MHC) genes are central to vertebrate immune response and are believed to be under balancing selection by pathogens. This hypothesis has been supported by observations of extremely high polymorphism, elevated nonsynonymous to synonymous base pair substitu...

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Detalhes bibliográficos
Main Authors: Kamath, Pauline L, Getz, Wayne M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126738/
https://ncbi.nlm.nih.gov/pubmed/21592397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-11-128
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