Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERRβ

The orphan nuclear receptor ERRβ is expressed in undifferentiated trophoblast stem cell lines and extraembryonic ectoderm, and genetic ablation of ERRβ results in abnormal trophoblast proliferation and precocious differentiation toward the giant cell lineage. Here, we show that the synthetic estroge...

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Detalhes bibliográficos
Main Authors: Tremblay, Gilles B., Kunath, Tilo, Bergeron, Denis, Lapointe, Line, Champigny, Céline, Bader, Jo-Ann, Rossant, Janet, Giguère, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC312665/
https://ncbi.nlm.nih.gov/pubmed/11297507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.873401
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