Metabolism and Disposition of 3,4-Methylenedioxymethamphetamine (“Ecstasy”) in Baboons after Oral Administration: Comparison with Humans Reveals Marked Differences

The baboon is potentially an attractive animal for modeling 3,4-methylenedioxymethamphetamine (MDMA) effects in humans. Baboons self-administer MDMA, are susceptible to MDMA neurotoxicity, and are suitable for positron emission tomography, the method most often used to probe for MDMA neurotoxicity i...

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Detalles Bibliográficos
Main Authors: Mueller, Melanie, Goodwin, Amy K., Ator, Nancy A., McCann, Una D., Ricaurte, George A.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Metabolism, Transport, and Pharmacogenomics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126644/
https://ncbi.nlm.nih.gov/pubmed/21493752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.180612
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