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Pleiotropic Action of AP-1 in v-Src-Transformed Cells

The activation of AP-1 is a hallmark of cell transformation by tyrosine kinases. In this study, we characterize the role of AP-1 proteins in the transformation of chicken embryo fibroblasts (CEF) by v-Src. In normal CEF, the expression of a dominant negative mutant of c-Jun (TAM67) induced senescenc...

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Autors principals: Wang, Lizhen, Rodrigues, Natalie A., Wu, Ying, Maslikowski, Bart M., Singh, Nishi, Lacroix, Samantha, Bédard, Pierre-André
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126506/
https://ncbi.nlm.nih.gov/pubmed/21507983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01013-10
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