Evolution of Drug-Resistant Viral Populations during Interruption of Antiretroviral Therapy

Analysis of a large number of HIV-1 genomes at multiple time points after antiretroviral treatment (ART) interruption allows determination of the evolution of drug-resistant viruses and viral fitness in vivo in the absence of drug selection pressure. Using a parallel allele-specific sequencing (PASS...

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Autori principali: Wang, Dongning, Hicks, Charles B., Goswami, Neela D., Tafoya, Emi, Ribeiro, Ruy M., Cai, Fangping, Perelson, Alan S., Gao, Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Genetic Diversity and Evolution
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126484/
https://ncbi.nlm.nih.gov/pubmed/21490094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02389-10
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