Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice

Chondrocyte hypertrophy is a mandatory step during endochondral ossification. Cbfa1-deficient mice lack hypertrophic chondrocytes in some skeletal elements, indicating that Cbfa1 may control hypertrophic chondrocyte differentiation. To address this question we generated transgenic mice expressing Cb...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Takeda, Shu, Bonnamy, Jean-Pierre, Owen, Michael J., Ducy, Patricia, Karsenty, Gerard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2001
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312629/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11230154/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.845101
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