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A 128-Base-Pair Sequence Containing the pac1 and a Presumed Cryptic pac2 Sequence Includes cis Elements Sufficient To Mediate Efficient Genome Maturation of Human Cytomegalovirus

Herpesvirus DNA replication proceeds via concatemeric replicative intermediates that are comprised of head-to-tail linked genomes. Genome maturation is carried out by the terminase, an enzyme complex that mediates both the insertion of concatemer DNA into capsids and its subsequent cleavage to relea...

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Hlavní autoři: Wang, Jian Ben, McVoy, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126264/
https://ncbi.nlm.nih.gov/pubmed/21345955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02307-10
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