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Activities of ICP0 Involved in the Reversal of Silencing of Quiescent Herpes Simplex Virus 1

ICP0 is a transcriptional activating protein required for the efficient replication and reactivation of latent herpes simplex virus 1 (HSV-1). Multiple regions of ICP0 contribute its activity, the most prominent of which appears to be the RING finger, which confers E3 ubiquitin ligase activity. A re...

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Autors principals: Ferenczy, Michael W., Ranayhossaini, Daniel J., DeLuca, Neal A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126212/
https://ncbi.nlm.nih.gov/pubmed/21411540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02265-10
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