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Human Adenovirus Type 5 Induces Cell Lysis through Autophagy and Autophagy-Triggered Caspase Activity

Oncolytic adenoviruses, such as Delta-24-RGD, are promising therapies for patients with brain tumor. Clinical trials have shown that the potency of these cancer-selective adenoviruses should be increased to optimize therapeutic efficacy. One potential strategy is to increase the efficiency of adenov...

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Detalhes bibliográficos
Main Authors: Jiang, Hong, White, Erin J., Ríos-Vicil, Christian I., Xu, Jing, Gomez-Manzano, Candelaria, Fueyo, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126198/
https://ncbi.nlm.nih.gov/pubmed/21367888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02032-10
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